Дрим судится с Миссисипи
Aug. 26th, 2025 01:27 pm![[personal profile]](https://www.dreamwidth.org/img/silk/identity/user.png)
На новость навела
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Этот штат ратифицировал 13 поправку, отменяющую рабство, лишь в 2013 году. (это заметка не про рабство - это про работу юридической системы в этом штате. Странные они)
I'll start with the tl;dr summary to make sure everyone sees it and then explain further: As of September 1, we will temporarily be forced to block access to Dreamwidth from all IP addresses that geolocate to Mississippi for legal reasons. This block will need to continue until we either win the legal case entirely, or the district court issues another injunction preventing Mississippi from enforcing their social media age verification and parental consent law against us.
Mississippi residents, we are so, so sorry. We really don't want to do this, but the legal fight we and Netchoice have been fighting for you had a temporary setback last week. We genuinely and honestly believe that we're going to win it in the end, but the Fifth Circuit appellate court said that the district judge was wrong to issue the preliminary injunction back in June that would have maintained the status quo and prevented the state from enforcing the law requiring any social media website (which is very broadly defined, and which we definitely qualify as) to deanonymize and age-verify all users and obtain parental permission from the parent of anyone under 18 who wants to open an account.
Netchoice took that appellate ruling up to the Supreme Court, who declined to overrule the Fifth Circuit with no explanation -- except for Justice Kavanaugh agreeing that we are likely to win the fight in the end, but saying that it's no big deal to let the state enforce the law in the meantime.
Needless to say, it's a big deal to let the state enforce the law in the meantime. The Mississippi law is a breathtaking state overreach: it forces us to verify the identity and age of every person who accesses Dreamwidth from the state of Mississippi and determine who's under the age of 18 by collecting identity documents, to save that highly personal and sensitive information, and then to obtain a permission slip from those users' parents to allow them to finish creating an account. It also forces us to change our moderation policies and stop anyone under 18 from accessing a wide variety of legal and beneficial speech because the state of Mississippi doesn't like it -- which, given the way Dreamwidth works, would mean blocking people from talking about those things at all. (And if you think you know exactly what kind of content the state of Mississippi doesn't like, you're absolutely right.)
Needless to say, we don't want to do that, either. Even if we wanted to, though, we can't: the resources it would take for us to build the systems that would let us do it are well beyond our capacity. You can read the sworn declaration I provided to the court for some examples of how unworkable these requirements are in practice. (That isn't even everything! The lawyers gave me a page limit!)
Unfortunately, the penalties for failing to comply with the Mississippi law are incredibly steep: fines of $10,000 per user from Mississippi who we don't have identity documents verifying age for, per incident -- which means every time someone from Mississippi loaded Dreamwidth, we'd potentially owe Mississippi $10,000. Even a single $10,000 fine would be rough for us, but the per-user, per-incident nature of the actual fine structure is an existential threat. And because we're part of the organization suing Mississippi over it, and were explicitly named in the now-overturned preliminary injunction, we think the risk of the state deciding to engage in retaliatory prosecution while the full legal challenge continues to work its way through the courts is a lot higher than we're comfortable with. Mississippi has been itching to issue those fines for a while, and while normally we wouldn't worry much because we're a small and obscure site, the fact that we've been yelling at them in court about the law being unconstitutional means the chance of them lumping us in with the big social media giants and trying to fine us is just too high for us to want to risk it. (The excellent lawyers we've been working with are Netchoice's lawyers, not ours!)
All of this means we've made the extremely painful decision that our only possible option for the time being is to block Mississippi IP addresses from accessing Dreamwidth, until we win the case. (And I repeat: I am absolutely incredibly confident we'll win the case. And apparently Justice Kavanaugh agrees!) I repeat: I am so, so sorry. This is the last thing we wanted to do, and I've been fighting my ass off for the last three years to prevent it. But, as everyone who follows the legal system knows, the Fifth Circuit is gonna do what it's gonna do, whether or not what they want to do has any relationship to the actual law.
We don't collect geolocation information ourselves, and we have no idea which of our users are residents of Mississippi. (We also don't want to know that, unless you choose to tell us.) Because of that, and because access to highly accurate geolocation databases is extremely expensive, our only option is to use our network provider's geolocation-based blocking to prevent connections from IP addresses they identify as being from Mississippi from even reaching Dreamwidth in the first place. I have no idea how accurate their geolocation is, and it's possible that some people not in Mississippi might also be affected by this block. (The inaccuracy of geolocation is only, like, the 27th most important reason on the list of "why this law is practically impossible for any site to comply with, much less a tiny site like us".)
If your IP address is identified as coming from Mississippi, beginning on September 1, you'll see a shorter, simpler version of this message and be unable to proceed to the site itself. If you would otherwise be affected, but you have a VPN or proxy service that masks your IP address and changes where your connection appears to come from, you won't get the block message, and you can keep using Dreamwidth the way you usually would.
On a completely unrelated note while I have you all here, have I mentioned lately that I really like ProtonVPN's service, privacy practices, and pricing? They also have a free tier available that, although limited to one device, has no ads or data caps and doesn't log your activity, unlike most of the free VPN services out there. VPNs are an excellent privacy and security tool that every user of the internet should be familiar with! We aren't affiliated with Proton and we don't get any kickbacks if you sign up with them, but I'm a satisfied customer and I wanted to take this chance to let you know that.
Again, we're so incredibly sorry to have to make this announcement, and I personally promise you that I will continue to fight this law, and all of the others like it that various states are passing, with every inch of the New Jersey-bred stubborn fightiness you've come to know and love over the last 16 years. The instant we think it's less legally risky for us to allow connections from Mississippi IP addresses, we'll undo the block and let you know.
Чтобы устранить российскую пропаганду и выстроить польско-украинские отношения на настоящем партнерстве и взаимном уважении, чувствительности, я считаю, что мы должны в законопроекте закрепить однозначный лозунг: "стоп бандеризму". А также в Уголовном кодексе – приравнять бандеровский символ к символам, которые соответствуют немецкому национал-социализму, общеизвестному как нацизм, советскому коммунизму, и внести изменения в закон об Институте национальной памяти – Комиссии по преследованию преступлений против польского народа в части, касающейся преступлений ОУН-УПА.
Я считаю, что мы должны достичь здесь определенной социальной справедливости. Поляки в своей стране должны быть по крайней мере на равных с нашими гостями из Украины. Для меня это принципиальный вопрос, поэтому я не подписал закон о помощи гражданам Украины в таком виде.
( результат )
$ grep -i insulin human_swissprot_proteins.tsvА вот скрипт, показывающий структуру указанного протеина: get_protein_sequence.py. Опробуем на инсулине:
F8WCM5 Insulin, isoform 2 INS-IGF2
O00425 Insulin-like growth factor 2 mRNA-binding protein 3 IGF2BP3
O14654 Insulin receptor substrate 4 IRS4
O15503 Insulin-induced gene 1 protein INSIG1
P01308 Insulin INS
P01344 Insulin-like growth factor 2 IGF2
P05019 Insulin-like growth factor 1 IGF1
P06213 Insulin receptor INSR
P08069 Insulin-like growth factor 1 receptor IGF1R
P08833 Insulin-like growth factor-binding protein 1 IGFBP1
P09565 Putative insulin-like growth factor 2-associated protein N/A
P14616 Insulin receptor-related protein INSRR
P14735 Insulin-degrading enzyme IDE
P17936 Insulin-like growth factor-binding protein 3 IGFBP3
P18065 Insulin-like growth factor-binding protein 2 IGFBP2
P22692 Insulin-like growth factor-binding protein 4 IGFBP4
P24592 Insulin-like growth factor-binding protein 6 IGFBP6
P24593 Insulin-like growth factor-binding protein 5 IGFBP5
P35568 Insulin receptor substrate 1 IRS1
P35858 Insulin-like growth factor-binding protein complex acid labile subunit IGFALS
P51460 Insulin-like 3 INSL3
P61371 Insulin gene enhancer protein ISL-1 ISL1
Q01101 Insulinoma-associated protein 1 INSM1
Q14641 Early placenta insulin-like peptide INSL4
Q16270 Insulin-like growth factor-binding protein 7 IGFBP7
Q6B9Z1 Insulin growth factor-like family member 4 IGFL4
Q6U949 Putative insulin-like growth factor 2 antisense gene protein IGF2-AS
Q6UW32 Insulin growth factor-like family member 1 IGFL1
Q6UWQ7 Insulin growth factor-like family member 2 IGFL2
Q6UXB1 Insulin growth factor-like family member 3 IGFL3
Q86XT9 Insulin-like growth factor-binding protein 3 receptor TMEM219
Q8TDV5 Glucose-dependent insulinotropic receptor GPR119
Q8WX77 Insulin-like growth factor-binding protein-like 1 IGFBPL1
Q96A47 Insulin gene enhancer protein ISL-2 ISL2
Q96T92 Insulinoma-associated protein 2 INSM2
Q9NZI8 Insulin-like growth factor 2 mRNA-binding protein 1 IGF2BP1
Q9Y4H2 Insulin receptor substrate 2 IRS2
Q9Y581 Insulin-like peptide INSL6 INSL6
Q9Y5Q6 Insulin-like peptide INSL5 INSL5
Q9Y5U4 Insulin-induced gene 2 protein INSIG2
Q9Y6M1 Insulin-like growth factor 2 mRNA-binding protein 2 IGF2BP2
$ python3 get_protein_sequence.py P01308Каждая буква обозначает аминокислоту:
Fetching protein sequence for UniProt accession: P01308
UniProt data retrieved for P01308: Insulin
Saved sequence to protein_sequences.fasta
$ cat protein_sequences.fasta
>P01308 | Insulin | UniProt Protein Sequence
MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN
1-е основание | 2-е основание | 3-е основание | |||||||
---|---|---|---|---|---|---|---|---|---|
U | C | A | G | ||||||
U | UUU | (Phe) Фенилаланин | UCU | (Ser) Серин | UAU | (Tyr) Тирозин | UGU | (Cys) Цистеин | U |
UUC | UCC | UAC | UGC | C | |||||
UUA | (Leu) Лейцин | UCA | UAA | Стоп | UGA | Стоп | A | ||
UUG | UCG | UAG | Стоп | UGG | (Trp) Триптофан | G | |||
C | CUU | CCU | (Pro) Пролин | CAU | (His) Гистидин | CGU | (Arg) Аргинин | U | |
CUC | CCC | CAC | CGC | C | |||||
CUA | CCA | CAA | (Gln) Глутамин | CGA | A | ||||
CUG | CCG | CAG | CGG | G | |||||
A | AUU | (Ile) Изолейцин | ACU | (Thr) Треонин | AAU | (Asn) Аспарагин | AGU | (Ser) Серин | U |
AUC | ACC | AAC | AGC | C | |||||
AUA | ACA | AAA | (Lys) Лизин | AGA | (Arg) Аргинин | A | |||
AUG | (Met) Метионин | ACG | AAG | AGG | G | ||||
G | GUU | (Val) Валин | GCU | (Ala) Аланин | GAU | (Asp) Аспарагиновая кислота | GGU | (Gly) Глицин | U |
GUC | GCC | GAC | GGC | C | |||||
GUA | GCA | GAA | (Glu) Глутаминовая кислота | GGA | A | ||||
GUG | GCG | GAG | GGG | G |
Полный стоп перекачки нефти на неопределенный срок. Привет от Птиц СБС.
Нефтеперекачивающая станция "Никольское" (Тамбовская область, РФ) дефлорирована Птицами 14 полка Сил беспилотных систем ВСУ.
Это последнее нападение на нашу энергетическую безопасность возмутительно и неприемлемо!.
[...]
Брюссель и Киев уже три с половиной года пытаются втянуть Венгрию в войну в Украине, и все более частые нападения Украины на нашу энергетическую безопасность также направлены на это.
[...]
Напоследок напоминаем украинским политикам: электроэнергия из Венгрии играет ключевую роль в энергоснабжении Украины
Национальная традиция правобережного казачества предполагает, что оно сражается максимум пока ему платят деньги.
Гораздо чаще начинает требовать еще денег на полпути.
Я конечно полистаю историю, но навскидку припомнить никаких бесплатных войн не могу.